Triple Monoamine Reuptake Inhibitor
Tesofensine
A small-molecule triple monoamine reuptake inhibitor studied for appetite suppression through a central nervous system pathway entirely separate from incretin receptor agonism, often researched alongside GLP-1 compounds as a mechanistically distinct comparator.
Price at Core Power Peptides
80 mg vial · $1.36/mg
Prices checked Sep 29, 2026.
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Mechanism
Blocks reuptake of dopamine, noradrenaline, and serotonin, increasing their availability in appetite-regulating regions of the hypothalamus. Because it works upstream of the gut-hormone pathways that GLP-1 and dual agonists target, researchers use it to study whether combining central and peripheral appetite pathways produces additive effects.
Research focus
- Category
- Triple Monoamine Reuptake Inhibitor
- Sequence length
- Small molecule
- Research status
- In clinical trials
- Best for
- Non-incretin appetite-pathway research
Related compounds
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