All compounds

GLP-1 Receptor Agonist

Liraglutide

A once-daily GLP-1 receptor agonist and the first incretin-mimetic to reach approval for chronic weight management, now used as the historical baseline against which longer-acting analogs are measured.

Not currently stocked at Core Power Peptides. Semaglutide is the closest single-pathway GLP-1 compound in stock.

Mechanism

Activates the GLP-1 receptor with a fatty-acid side chain that promotes albumin binding, extending its half-life relative to native GLP-1 while still requiring daily dosing to maintain steady exposure. Research on liraglutide established much of the early dose-response and gastric-emptying data later applied to weekly agonists.

Research focus

Daily-dosing pharmacokineticsEarly incretin dose-response dataComparator baseline for newer agonists
Category
GLP-1 Receptor Agonist
Sequence length
31 amino acids
Research status
Approved analog exists
Best for
A baseline GLP-1 comparator for newer incretin compounds

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Reviewed by the Peptides For Weight Loss editorial team. See our editorial standards and sourcing methodology.