GIP / GLP-1 / Glucagon Triple Agonist
Retatrutide
A triple-receptor agonist that layers glucagon receptor activity on top of GIP and GLP-1 signaling, currently the most mechanistically aggressive compound in active late-stage trials for this class.
Not currently stocked at Core Power Peptides. Tirzepatide and Mazdutide are the closest multi-receptor agonists in stock.
Mechanism
The added glucagon receptor agonism is theorized to increase energy expenditure alongside the appetite and glycemic effects shared with dual agonists, a combination researchers are studying for its effect on lean-mass preservation during weight reduction.
Research focus
Energy expenditureHepatic lipid handlingLean-mass preservation
- Category
- GIP / GLP-1 / Glucagon Triple Agonist
- Sequence length
- 39 amino acids
- Research status
- In clinical trials
- Best for
- Three-receptor (GIP, GLP-1, glucagon) mechanism research
Related compounds
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